The human skin is the largest organ which consists of several layers of cells, fibres and fats1.
The Epidermis or widely known the skin barrier is the outermost layer. It is made of cells called corneocytes which are surrounded by a viscous matrix of lipid and water. This lipid matrix is composed of ceramides (approximately 50%), free fatty acids (10%- 20%), and cholesterol (25%)2
The function of the skin barrier is to support and protect the deeper skin layers. External factors such as pollution, ultraviolet light and chemical irritation can disrupt the skin barrier resulting in loss of water, a key feature in dry and eczema- prone skin3
Therefore, skin hydration is a key to maintain a healthy intact skin barrier preventing risk of eczema episodes.
the National Institute for Health and Care Excellence (NICE) Guidelines states that patients with dry eczema prone- skin should hydrate their skin up to four times a day using an unperfumed emollients4
For a Medical visit to learn more about our products and receive samples, please contact: firstname.lastname@example.org
For stock enquiries and have CeraVe at your pharmacy contact: the commercial email to For stock enquiries and to list CeraVe at your pharmacy contact: UKIACDCustomerServices@loreal.com
The formulation of skin-identical ceramides with MultiVesicular Emulsion Technology (MVE) was the birth of CeraVe. We have the only line of skincare products with a unique blend of three essential ceramides, plus patented MVE technology that gradually releases our ceramide-enriched formula over an extended period. MVE is like a sphere with a series of layers that slowly dissolves, releasing the ingredients into your skin. The product continues to work after it is applied, hydrating your skin all day in just one use
FIGURE 1: Traditional emulsion ingredient release vs MVE ingredient release
This system along with our unique combination of skin-identical ceramides, helps replenish your skin’s existing ceramides,
Aside from the MVE Technology and the replenished lipids, CeraVe Moisturising Cream and Lotion also contain other key ingredients such as hyaluronic acid and glycerin; both work to hydrate the skin and form a film to prevent further water loss.
The CeraVe emollients range is light-weight, non-greasy, hypoallergic and developed with dermatologist.
CeraVe is the #1 recommended brand by dermatologists in the United States5
1Sahle FF, Gebre-Mariam T, Dobner B, Wohlrab J, Neubert RHH. Skin diseases associated with the depletion of stratum corneum lipids and stratum corneum lipid substitution therapy. Skin Pharmacol Physiol. 2015;28:42-55. 2Moore JM, Rawlings AV. The chemistry, function & (patho)physiology of stratum corneum barrier ceramides. Int J Cosmetic Sci. doi:10.111/ics.12399. 3Del Rosso JQ, Levin J. The clinical relevance of maintaining the functional integrity of the stratum corneum in both healthy and disease-affected skin. J Clin Aesth Dermatol. 2011;4(91):1-22. 4National Institute for Health and Care Excellence (NICE) guidelines: Atopic eczema in under 12s: diagnosis and management. 02 March 2020. 5https://www.cerave.com/about-cerave